Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

THE SILENT FIRE

Chronic Inflammation Is Burning Through Your Body Undetected

The joint pain, the fatigue, the brain fog, the stubborn weight. Inflammation is often the hidden driver behind symptoms that seem unrelated.
Chronic inflammation | Nepute Wellness
THE COMPOUNDING COST

Inflammation Does Not Plateau. It Escalates.

Acute inflammation heals. Chronic inflammation destroys. When the inflammatory response stays activated, it damages tissues, disrupts hormones, impairs cognition, promotes insulin resistance, and accelerates aging at the cellular level. Research increasingly identifies chronic inflammation as a central driver behind most degenerative conditions.
Systemic inflammation disrupts hormone signaling and promotes insulin resistance
Inflammatory compounds cross the blood-brain barrier, impairing cognition
Chronic inflammatory pathways accelerate cellular aging across every system

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Detox Protocols
Food Sensitivity Testing
Gut Health & Microbiome Testing
Comprehensive Blood Panels
INFLAMMATION SCIENCE

Why Your Body's Alarm System Refuses to Turn Off

Inflammation is supposed to be temporary. Injury, infection, threat: your immune system responds, repairs, and stands down. Chronic inflammation means the stand-down signal never fires. The causes range from gut dysfunction to food sensitivities to toxin exposure to metabolic imbalance. Identifying the source is essential.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Your Immune System

An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.

A compromised gut barrier allows particles into circulation that trigger persistent immune activation.

Delayed immune reactions to foods create low-grade inflammation that persists because the trigger is consumed daily without your knowledge.

Insulin resistance, excess visceral fat, and blood sugar dysregulation all generate inflammatory signals that perpetuate a vicious cycle.

WHEN INFLAMMATION GOES UNCHECKED

The Fire You Cannot See Is the Most Dangerous One

Understanding Your Immune System
An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.
ROOT CAUSE, NOT SYMPTOM MANAGEMENT

Anti-Inflammatories Suppress Symptoms. Testing Finds the Source.

NSAIDs, turmeric supplements, and anti-inflammatory diets manage symptoms. They do not identify why your body is inflamed. Comprehensive testing measures inflammatory markers, assesses gut health, identifies food sensitivities, and reveals metabolic factors fueling the fire so the actual source can be addressed.
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COOL THE FIRE

Imagine Your Body Free from Chronic Inflammation

When inflammation sources are identified and addressed, patients often experience transformation across multiple symptoms:

Joint Comfort

That constant aching and stiffness often resolves when systemic inflammation decreases.

Natural Energy

Energy returns when your body isn't fighting constant inflammation.

Inflammation Fog Lifted

Brain fog lifts as inflammatory signals to the brain decrease.

Inflammation Weight Shifts

Stubborn weight often responds once inflammatory hormonal signals normalize.

Inflammation Skin Cleared

Many skin conditions improve dramatically with reduced systemic inflammation.

Feel Younger

Inflammation accelerates aging - cooling the fire often helps slow that trajectory.
Detox protocol | Nepute Wellness

Detox Protocols

STRUCTURED DETOXIFICATION SUPPORT

Food intolerance | Nepute Wellness

Food Sensitivity Testing

IDENTIFY YOUR HIDDEN TRIGGERS

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Gut Health & Microbiome Testing

DIGESTIVE AND MICROBIOME ANALYSIS

Blood panel | Nepute Wellness

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

THE FIRE RESOLVED

Others Found Their Inflammation Source and So Can You

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Dr. Nepute and his team deliver a truly exceptional level of care that stands far above the rest. The advanced, results-driven approach they take is both comprehensive and refreshingly effective. Every aspect of the patient experience – from the in-depth consultations to the clear, consistent communication – is handled with an impressive attention to detail. What sets Dr. Nepute apart is not only his deep clinical expertise, but also his commitment to patient education and empowerment. You leave feeling informed, supported, and genuinely cared for. This is integrative care at its finest!
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Mary Lynn Papin
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The staff and doctors are great and friendly! Always making sure they are working on whatever is bothering me along with what I’m being treated for. I look forward to going every week!
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Meg H
Google Review
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A place where the doctors care about your true health and help you fix it naturally! Always been nothing but pleased when going here. They work with you on everything to make sure you are healthy and don’t neglect yourself because of money or time. My son did a brain balance program there (no longer there though) and it helped him tremendously. Chiropractic care helps with any issue you may have! They always have the newest technology or therapy (like the laser that I recently used after a car accident I had) to help you be out of pain. I have carpal tunnel and regular adjustments keep my hand from falling asleep at night. pain goes away also. Highly recommend!
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Lisa Siebel
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I am a patient at Dr Eric Nepute ‘s office Nepute Wellness Center in St Louis MO. I can’t say enough good things about this practice. From the time you walk in the door and are greeted at the front desk by Haley and Deidra. They are so friendly and helpful. So very organized and always get back to you promptly with answers for your questions. The staff is very friendly and take care of you like family. As far as Dr. Nepute he brought me out of one of the worst times of my life. Last summer at the end of July 2025 I began to have tremors and shaking. I had been to several doctors who had no idea how to help me. Dr Nepute knew right away what was causing the shakiness and treated me. Within 2 weeks the tremors had stopped. My vagus nerve was the cause. I am continuing to work with Dr Nepute on my overall health and other issues. He is so patient and takes his time with you to explain your test results and gives solutions on how to improve your health. He is very thorough and knowledgeable. He truly is the most caring doctor I know and really wants to see his patients get better and enjoy a healthy life. He is one in a million.
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Eileen Decker
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The best wellness center around St louis
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Dhrutika Patel
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Knowledgeable and caring team of professionals!
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Candice Ward
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If you want HEALTHcare instead of SICKcare, go see Dr. Nepute and his staff. They get to the root of your issues to FIX the problem so you can heal. I wish I would have known about him sooner!
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Jane The Patriot
Google Review
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Nepute Wellness Center is a place to achieve great optimal health and get down to the root cause of any health issues you may have. The other docs in the office are great along with a friendly staff.
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Amanda Prosser
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The staff was great, I was really impressed, they listen to my concern and gave me excellent care.
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Stephanie Ennis
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Everyone is extremely helpful and display a very high level of concern and professionalism.
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Pam Davis
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Feel so blessed to have found this place ! Since I’ve been going here I’m off all my meds feel better than I have in years! Taking supplements that have worked better than the prescriptions that masked and created more adverse symptoms! Friendliest staff ever ! Have sent many family and friends and all have thanked me multiple times ! If you’re looking to find answers to your health issues aches and pains instead of more medications and surgeries this is the place . God bless you all for your commitment to better health naturally !
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Margaret Wienstroer
Google Review
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Everyone is very nice, friendly, and helpful. They take the time to explain things if you need it. The doctors are very good about listening to you and helping you to feel better. They do more than adjustments.
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Carol Tinnea
Google Review
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I have never been to a more thorough group of doctors and team! Love this place and I haven’t felt this good in years! Thank you for addressing the root causes of my issues! Highly Recommend!
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Jennifer Layton
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Has helped my back and overall health tremendously
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Sandra Lynch
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Dr Eric Nepute and staff are amazing and truly care about getting to the( Root ) of what is going on and get you the help you need. Finally! after years of health issues I now know my root cause and getting some help and feeling great already ❤️
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Paula Wells
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INFLAMMATION INVESTIGATION

How We Find What Is Fueling Your Body's Inflammatory Response

We measure CRP, homocysteine, and other inflammatory markers alongside gut health testing, food sensitivity panels, and a full metabolic workup. Chronic inflammation has a source. Our job is finding it — not prescribing anti-inflammatories to mask it.

Chronic inflammation | Nepute Wellness
Systemic inflammation disrupts hormone signaling and promotes insulin resistance
Systemic inflammation disrupts hormone signaling and promotes insulin resistance
Chronic inflammation | Nepute Wellness
Inflammatory compounds cross the blood-brain barrier, impairing cognition
Inflammatory compounds cross the blood-brain barrier, impairing cognition
Chronic inflammation | Nepute Wellness
Chronic inflammatory pathways accelerate cellular aging across every system
Chronic inflammatory pathways accelerate cellular aging across every system
YOUR QUESTIONS ANSWERED

Common Questions About Chronic Inflammation

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.