Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

YOUR SKIN IS A WINDOW

Skin Problems Are Rarely Skin-Deep. They Signal Internal Dysfunction.

Eczema, psoriasis, acne, rashes, unexplained breakouts. You’ve tried creams, steroids, and explorelimination diets. The skin clears temporarily then flares again.
Skin problems | Nepute Wellness
ADDRESSING THE SURFACE

Creams and Steroids Suppress What Your Skin Is Trying to Tell You

Dermatology follows a pattern: identify the skin lesion, prescribe a topical or systemic suppressant, manage flares indefinitely. Steroid creams, immunosuppressants, biologics -- each targets the symptom at the surface. But your skin is an organ of elimination and explorexpression.
Topical steroids thin skin over time and suppress the immune signal without resolving it
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Food sensitivities trigger inflammatory skin reactions that topicals cannot address

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Detox Protocols
Food Sensitivity Testing
Gut Health & Microbiome Testing
Comprehensive Blood Panels
THE GUT-SKIN AXIS

How Your Digestive System Controls Your Skin's Behavior

Research has established a direct communication pathway between your gut and your skin called the gut-skin axis. When your gut microbiome is disrupted, when the intestinal lining is compromised, or when food triggers inflammation, your skin is often the first organ to display the consequences.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Your Immune System

An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.

An imbalanced gut microbiome produces inflammatory metabolites that circulate through your bloodstream and activate skin immune cells.

Delayed food sensitivities create systemic inflammation that manifests on the skin 24 to 72 hours after eating.

Hormonal imbalances -- particularly elevated androgens, cortisol dysregulation, and estrogen dominance -- directly influence skin oil production, cell turnover, and inflammation. Balancing these hormones from within often resolves what topical approaches cannot.

WHEN SKIN PROBLEMS GO INTERNAL

Chronic Skin Inflammation Signals Dysfunction You Can't See

Understanding Your Immune System
An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.
LOOK DEEPER THAN THE SURFACE

If Another Cream Could Fix This, It Would Have by Now

You've tried topical after topical. Some helped briefly. None resolved the underlying pattern. Our approach is Test, Don't Guess. We investigate the internal environment -- gut health, food sensitivities, hormones, inflammatory markers -- to identify what's driving your skin's behavior from inside.
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CLEAR SKIN

Imagine Your Skin Actually Healing

Picture clear, calm skin you are not covering up or apologizing for — the breakouts, redness, and flares gone because the internal triggers driving them have finally been identified and resolved.

Clearer Skin

Skin that heals and stays clear, not temporary improvement followed by flares.

Calm Inflammation

Inflammation resolves as internal triggers are removed.

Physical Comfort

The itching, burning, and discomfort subside.

Confidence Restored

Feel good about your skin and stop hiding or compensating.

Reduced Medication

Reduce or eliminate dependence on topical steroids and medications.

Clear Understanding

Know exactly what's causing your skin to react and how you're addressing it.
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Detox Protocols

STRUCTURED DETOXIFICATION SUPPORT

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Food Sensitivity Testing

IDENTIFY YOUR HIDDEN TRIGGERS

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Gut Health & Microbiome Testing

DIGESTIVE AND MICROBIOME ANALYSIS

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Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

REAL PATIENT EXPERIENCES

People Whose Skin Cleared When the Internal Cause Was Found

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My experience at my initial appointment was amazing! The office process ran smoothly, they explained everything including pricing, the medical assistant doing all of my testing was compassionate and kind And answered all of my questions, and the doctor that did my chiropractic adjustment provided me with some great insights about my x-rays as well as about the adjustment she was doing. I left feeling no pain in my neck And hopeful that we will get to the bottom of my symptoms.
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Gina Prinzavalli
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Dr Nepute’s vitamins particularly the D3 and Zinc, have been life changing for me! My blood tests showed a D3 number of a #4…That’s unheard-of low. I took vitamins from Walmart and they did nothing. I took Dr.. Nepute’s vitamins for 2 years, and now my D3 number is a whopping #81. I feel so much better with so much more energy. Thanks Dr. Nepute!
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Janie Cohoon
Google Review
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I recently stopped into Nepute Wellness and as always…they were excellent.
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Luke Adler
Google Review
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Great atmosphere Staff is super friendly, very knowledgeable and extremely accommodating. No matter how busy they are, you always receive one on one attention. Nepute’s Office is my Family’s primary care provider. 5 children from 18 all the way down to 3. Highly recommend a Dr’s office who absolutely does not help address you like a just another patient who believes that a pill or surgery may help support recovery from all. Believe it or not, our bodies do have the ability to heal themselves. We also actually have our own immune systems that fight against diseases. It’s just a matter of having a Dr who can assist in your personal direction to bring your body’s full potential to flourishing. I’m very happy my wife found Dr Nepute when she did.
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Scottie Kohlberg
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My experience was excellent with Nepute Wellness Center. The staff was very nice!
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Anton Arch
Google Review
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This place has helped my wife and I so much. They have a passion fur helping people.
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Ben Neely
Google Review
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I really don’t know where to start! This place is incredible! From the front desk, to the entire staff. Very knowledgeable, & friendly Dr’s. Chelsey, & Jacob have helped to restore my painful condition, & my health. Two of the best therapists I have ever seen. I feel like I have my life back again. I highly recommend Nepute Wellness to everyone. Thank you all.
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Christopher Artis
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People are always so polite and helpful. Making you feel comfortable your entire visit. Lots of smiles.
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Kelley Kull
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They are all great and friendly and professional
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Rhonda Burk
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Very refreshing to work with competent medical people
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Buzz Mendonsa
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1 of the best natural health healing places I believe that exists . Thankyou for your work
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Ronald Snyder
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Amazing care for our young athlete! Dr. Rachel and her team are the best!
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Jonathan Shulan
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The level of care our family has received from the wonderful folks at Nepute Wellness has been unmatched elsewhere. From the kind lady (Jill) answering the phone to the professional care of the front desk personnel it is a joy to interact with them. Our family of 6 drives approximately 8 hours, round trip, to see Dr Nepute and his amazing staff! We love his proactive approach and willingness to test instead of guess.
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Sharla Bowser
Google Review
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I appreciate so much the wisdom and knowledge Dr. Patrick accessed my test results and relayed to me over the phone. We live to far away to run back and forth to the office. Thank you for helping me
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Patricia Duncan
Google Review
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Doc and his staff have completely changed my life. I have been suffering from chronic pain and inflamation. I have been going there for several years now. Dr. Eric, Dr. Rachel, Dr. Patric and staff have been extremely helpful. I have learned how to stay healthy and how to heal. I am in my sixties and very active. I plan on staying that way with the help of Nepute wellness. Over the years I have used traditional medicine only to be given pills that mask the pain. Neputi wellness has given me a holistic path to getting heathy and staying well. This type of wellness takes time. Have patience. You will be amazed ! Update 8/1/25 I just wanted to share that I have been taking the biolimitlist Neuro Reboot. My chronic pain has decreased to almost nothing. Especially in my lower back. This has allowed me to live the active life that I am accustomed to. I have been trying to avoid medications at all costs but was starting to give in. This product is working well. In my case, it took almost 60 days. But from then on, it was amazing. I noticed the first week I was sleeping better. The pain in my joints was starting to ease. My back, however, took a longer time. In my opinion, it is worth the money. And many thanks to doc and his amazing staff!
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Tony Frisella
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HOW WE INVESTIGATE SKIN CONDITIONS

Testing the Internal Environment Your Skin Reflects

Our skin-focused evaluation includes GI mapping for gut health, food sensitivity panels, comprehensive hormonal testing, inflammatory markers, and toxin screening. This reveals the internal triggers your dermatologist's exam couldn't detect because they we're never looking inside.

Skin problems | Nepute Wellness
Topical steroids thin skin over time and suppress the immune signal without resolving it
Topical steroids thin skin over time and suppress the immune signal without resolving it
Skin problems | Nepute Wellness
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Skin problems | Nepute Wellness
Food sensitivities trigger inflammatory skin reactions that topicals cannot address
Food sensitivities trigger inflammatory skin reactions that topicals cannot address
YOUR QUESTIONS ANSWERED

Common Questions About Skin Problems and Internal Health

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.