Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

YOUR SKIN IS A WINDOW

Skin Problems Are Rarely Skin-Deep. They Signal Internal Dysfunction.

Eczema, psoriasis, acne, rashes, unexplained breakouts. You’ve tried creams, steroids, and explorelimination diets. The skin clears temporarily then flares again.
Skin problems | Nepute Wellness
ADDRESSING THE SURFACE

Creams and Steroids Suppress What Your Skin Is Trying to Tell You

Dermatology follows a pattern: identify the skin lesion, prescribe a topical or systemic suppressant, manage flares indefinitely. Steroid creams, immunosuppressants, biologics -- each targets the symptom at the surface. But your skin is an organ of elimination and explorexpression.
Topical steroids thin skin over time and suppress the immune signal without resolving it
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Food sensitivities trigger inflammatory skin reactions that topicals cannot address

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Detox Protocols
Food Sensitivity Testing
Gut Health & Microbiome Testing
Comprehensive Blood Panels
THE GUT-SKIN AXIS

How Your Digestive System Controls Your Skin's Behavior

Research has established a direct communication pathway between your gut and your skin called the gut-skin axis. When your gut microbiome is disrupted, when the intestinal lining is compromised, or when food triggers inflammation, your skin is often the first organ to display the consequences.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Your Immune System

An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.

An imbalanced gut microbiome produces inflammatory metabolites that circulate through your bloodstream and activate skin immune cells.

Delayed food sensitivities create systemic inflammation that manifests on the skin 24 to 72 hours after eating.

Hormonal imbalances -- particularly elevated androgens, cortisol dysregulation, and estrogen dominance -- directly influence skin oil production, cell turnover, and inflammation. Balancing these hormones from within often resolves what topical approaches cannot.

WHEN SKIN PROBLEMS GO INTERNAL

Chronic Skin Inflammation Signals Dysfunction You Can't See

Understanding Your Immune System
An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.
LOOK DEEPER THAN THE SURFACE

If Another Cream Could Fix This, It Would Have by Now

You've tried topical after topical. Some helped briefly. None resolved the underlying pattern. Our approach is Test, Don't Guess. We investigate the internal environment -- gut health, food sensitivities, hormones, inflammatory markers -- to identify what's driving your skin's behavior from inside.
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CLEAR SKIN

Imagine Your Skin Actually Healing

Picture clear, calm skin you are not covering up or apologizing for — the breakouts, redness, and flares gone because the internal triggers driving them have finally been identified and resolved.

Clearer Skin

Skin that heals and stays clear, not temporary improvement followed by flares.

Calm Inflammation

Inflammation resolves as internal triggers are removed.

Physical Comfort

The itching, burning, and discomfort subside.

Confidence Restored

Feel good about your skin and stop hiding or compensating.

Reduced Medication

Reduce or eliminate dependence on topical steroids and medications.

Clear Understanding

Know exactly what's causing your skin to react and how you're addressing it.
Detox protocol | Nepute Wellness

Detox Protocols

STRUCTURED DETOXIFICATION SUPPORT

Food intolerance | Nepute Wellness

Food Sensitivity Testing

IDENTIFY YOUR HIDDEN TRIGGERS

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Gut Health & Microbiome Testing

DIGESTIVE AND MICROBIOME ANALYSIS

Blood panel | Nepute Wellness

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

REAL PATIENT EXPERIENCES

People Whose Skin Cleared When the Internal Cause Was Found

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This place is a SERIOUS ONE STOP SHOP! After first visit I noticed a significant difference in DECREASED pain. I am so glad I came here. Nepute attacks your issues from inside your body (nutrients, vitamins, minerals, etc.). As well as outside ( therapy ) at the same time. Before going to This WELLNESS CENTER, physical therapy, chiropractic, nutrition, weight loss, pain management, etc…. I happened to be somewhere around folks who were past and present clients/patients of Nepute. Once the Name “Nepute “ came up, they began sounding off about how great the practice was/services are. That made me excited about going… after first visit; THEY DID NOT DISAPPOINT, and SOME! The best wellness center I’ve ever been to in my life! And I have traveled overseas and throughout the United States (Retired Military). OUTSTANDING service that also provides educational info to assist with whatever you’re trying to do. THEY COVER IT ALL! PS very professional, knowledgeable, helpful and pleasant staff with state of the art/top of the line equipment, specialized testing, products, and SO, MUCH MORE! Too much to name all they do…. GO BY and SEE for yourself. You will be impressed! Thank you!
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TD Johnson
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Getting healthy!
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Pam Gonzalez
Google Review
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The staff at Nepute Wellness are by far the best at putting the patient first. They find the source of the problem instead of addressing the symptoms. The quality of my life has greatly improved. Have
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Jay Rowden
Google Review
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ALL staff members are very courteous and professional.
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John Huffman
Google Review
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Great to be back
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Vicki Seel
Google Review
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The wellness center really cares about there patients and there overall health and care
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Lee Chambers
Google Review
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1 of the best natural health healing places I believe that exists . Thankyou for your work
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Ronald Snyder
Google Review
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Dr. Nepute and his wellness center is absolutely amazing. If you’re looking for an all inclusive approach to getting answers for your health issues, this is where you want to be. Dr. Eric Nepute is extremely knowledgeable and gets to the root cause of the problem. I love the fact that he has multiple sources of ways to help and when he runs a blood work panel, it is very detailed and in depth in which other doctors just don’t do. I feel extremely lucky to have found him and really appreciate that we have someone like him in our area that loves to help people.
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Brenda Larson
Google Review
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What an amazing place! My granddaughter had an abnormal crawl and was over two years old and still not walking. After one adjustment, she started walking on her own two days later. Just amazing! I have gone here for many years and loved the care and service, but now it has even more special meaning to me!
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paula davis
Google Review
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The staff here are wonderful and patient! I always receive excellent care. I drove nearly 3 hours, one way, because of what they have to offer. I’ve been a patient for approximately 4 years.
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Greta Howard
Google Review
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I absolutely enjoy the staff. They are a wonderful group of people. I drive from Chesterfield to South County which is a long drive but well worth the drive. Great care, great staff.
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Sam Zito
Google Review
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Everyone is so professional and so friendly and they do care about your health place is amazing I would recommend anyone to go
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Tina Hammann
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Everyone was very friendly and helpful and from my first visit I felt better
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Miriam Yatim
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They are all wonderful
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Shonna Morrison
Google Review
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My son, who is only 20, was told by medical professionals that he had an autoimmune liver issue. They wanted to do a liver biopsy. Then, they told him they thought he had a pituitary tumor in his brain that would require brain surgery to remove. A friend recommended Nepute Wellness Center. Dr Nepute was able to diagnose his actual issues in 2 weeks with proper xrays and bloodwork. No autoimmune diseases. No brain tumor. It was a soccer injury from 1.5 yrs prior that had just gotten worse and caused his liver to overwork and a domino effect on his health and organs. We have been going there 3 weeks now and we are both feeling better. My son isn’t tired and can have full range of neck motion. His organ function is back to normal. Thanks Dr Nepute and team! All of you are wonderful!
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Jessica Turner
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HOW WE INVESTIGATE SKIN CONDITIONS

Testing the Internal Environment Your Skin Reflects

Our skin-focused evaluation includes GI mapping for gut health, food sensitivity panels, comprehensive hormonal testing, inflammatory markers, and toxin screening. This reveals the internal triggers your dermatologist's exam couldn't detect because they we're never looking inside.

Skin problems | Nepute Wellness
Topical steroids thin skin over time and suppress the immune signal without resolving it
Topical steroids thin skin over time and suppress the immune signal without resolving it
Skin problems | Nepute Wellness
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Skin problems | Nepute Wellness
Food sensitivities trigger inflammatory skin reactions that topicals cannot address
Food sensitivities trigger inflammatory skin reactions that topicals cannot address
YOUR QUESTIONS ANSWERED

Common Questions About Skin Problems and Internal Health

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.