Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

YOUR SKIN IS A WINDOW

Skin Problems Are Rarely Skin-Deep. They Signal Internal Dysfunction.

Eczema, psoriasis, acne, rashes, unexplained breakouts. You’ve tried creams, steroids, and explorelimination diets. The skin clears temporarily then flares again.
Skin problems | Nepute Wellness
ADDRESSING THE SURFACE

Creams and Steroids Suppress What Your Skin Is Trying to Tell You

Dermatology follows a pattern: identify the skin lesion, prescribe a topical or systemic suppressant, manage flares indefinitely. Steroid creams, immunosuppressants, biologics -- each targets the symptom at the surface. But your skin is an organ of elimination and explorexpression.
Topical steroids thin skin over time and suppress the immune signal without resolving it
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Food sensitivities trigger inflammatory skin reactions that topicals cannot address

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Detox Protocols
Food Sensitivity Testing
Gut Health & Microbiome Testing
Comprehensive Blood Panels
THE GUT-SKIN AXIS

How Your Digestive System Controls Your Skin's Behavior

Research has established a direct communication pathway between your gut and your skin called the gut-skin axis. When your gut microbiome is disrupted, when the intestinal lining is compromised, or when food triggers inflammation, your skin is often the first organ to display the consequences.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Your Immune System

An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.

An imbalanced gut microbiome produces inflammatory metabolites that circulate through your bloodstream and activate skin immune cells.

Delayed food sensitivities create systemic inflammation that manifests on the skin 24 to 72 hours after eating.

Hormonal imbalances -- particularly elevated androgens, cortisol dysregulation, and estrogen dominance -- directly influence skin oil production, cell turnover, and inflammation. Balancing these hormones from within often resolves what topical approaches cannot.

WHEN SKIN PROBLEMS GO INTERNAL

Chronic Skin Inflammation Signals Dysfunction You Can't See

Understanding Your Immune System
An evidence based overview of how your immune system works and why supporting immune health requires a root cause, whole person approach.
LOOK DEEPER THAN THE SURFACE

If Another Cream Could Fix This, It Would Have by Now

You've tried topical after topical. Some helped briefly. None resolved the underlying pattern. Our approach is Test, Don't Guess. We investigate the internal environment -- gut health, food sensitivities, hormones, inflammatory markers -- to identify what's driving your skin's behavior from inside.
Dre | Nepute Wellness
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CLEAR SKIN

Imagine Your Skin Actually Healing

Picture clear, calm skin you are not covering up or apologizing for — the breakouts, redness, and flares gone because the internal triggers driving them have finally been identified and resolved.

Clearer Skin

Skin that heals and stays clear, not temporary improvement followed by flares.

Calm Inflammation

Inflammation resolves as internal triggers are removed.

Physical Comfort

The itching, burning, and discomfort subside.

Confidence Restored

Feel good about your skin and stop hiding or compensating.

Reduced Medication

Reduce or eliminate dependence on topical steroids and medications.

Clear Understanding

Know exactly what's causing your skin to react and how you're addressing it.
Detox protocol | Nepute Wellness

Detox Protocols

STRUCTURED DETOXIFICATION SUPPORT

Food intolerance | Nepute Wellness

Food Sensitivity Testing

IDENTIFY YOUR HIDDEN TRIGGERS

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Gut Health & Microbiome Testing

DIGESTIVE AND MICROBIOME ANALYSIS

Blood panel | Nepute Wellness

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

REAL PATIENT EXPERIENCES

People Whose Skin Cleared When the Internal Cause Was Found

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Always a positive atmosphere.
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Larry Wylie
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No nonsense scientific approach to health. Fix the problem don’t hide the symptoms.
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Mark Wernowsky
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I appreciate how this office has a system to get you in and out , BUT they also have it well established to implement any question or concern and be flexible with your needs
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Jeannette Frey
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Awesome care. Everyone there is wonderful. They have helped me a lot!Very knowledgable too!That place is so good there are days it is so crowded!They take walkins too!I highly recommend them if you ha
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Lisa Lawson
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Dr. Eric Nepute and his associates have helped me immensely from the first time I almost crawled in his office with back pain to the present time when I am continuing to straighten my spine and improv
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Doug Smith
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Amazing experience, everyone is so kind and inviting, they make sure you understand everything that is happening and why they do what they do. I had to get IV’s for my treatment and from someone who hates needles they did fantastic and made me super comfortable and relatively painless!
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Lydia Rose
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The positive experience my family has had with the Nepute wellness Center has been amazing. The level of my families health has increased dramatically, I can’t imagine going anywhere else. I highly recommend!
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Nathan krauss
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Love Nepute Wellness! Tons of treatment options. Always leave feeling better. Staff is always friendly and awesome.
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Michael Turner
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Dr. Nepute Wellness Center is designed to be a diagnosis Center for the body. What I found to be especially unique is dr. Nepute is willing to cooperate and work with other doctors. In my son’s case, he is already working with a chiropractic specialists but does it have the other diagnostic tools. Dr. Nepute was able to get to the bottom of my son’s condition rather quickly and he prescribed a natural product that should start helping to solve the problem in my son’s body. Talk to the pool table leaves my son is suffering from leaky gut that has gone what is handed for many years. The products are moderately pricey but if these price will truly help my son get better than it’s worth it. I’ve spent about the same amount are viruses the past. But at least this time he’s only taking three products not 40 different vitamins. Some happy that it will be less of a burden on my son. I truly believe that if you have any kind of illness or if you have something that’s been playing you for a very long time you should go and see dr. Nepute and have him take a look. There initial patient see diagnostic check is relatively inexpensive. Go in have him check you out I’m sure you will be very happy to get started on a health and Wellness recovery.
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Rochelle Douglass McEathron
Google Review
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Very friendly very thorough. I give a better reverie later as I’m with them longer to see if the help with my stomach issues. Ok I have CB been with them a year now. My stomach issues have completely turned around I’m eating much better. My blood work is much better. I plan on sticking with them. If you do what they say. And talk to them about your problems they can help you.
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guy donahoo
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I don’t know where to start not only if I get into extreme new version of knowledge about my body but after setting up a long-term plan I’m already seeing results very early in the practice thank you guys so much
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William Duncan
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I have never been to a more thorough group of doctors and team! Love this place and I haven’t felt this good in years! Thank you for addressing the root causes of my issues! Highly Recommend!
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Jennifer Layton
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Everyone is very nice, friendly, and helpful. They take the time to explain things if you need it. The doctors are very good about listening to you and helping you to feel better. They do more than adjustments.
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Carol Tinnea
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Dr Nepute is amazing, so knowledgeable, and his team of professionals are so eager to help in any way! I feel blessed to get connected and have hope for my health to vastly improve!
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Vicky Abner
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Very good service and care. Highly recommend Nepute Wellness!
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Jean Schlueter
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HOW WE INVESTIGATE SKIN CONDITIONS

Testing the Internal Environment Your Skin Reflects

Our skin-focused evaluation includes GI mapping for gut health, food sensitivity panels, comprehensive hormonal testing, inflammatory markers, and toxin screening. This reveals the internal triggers your dermatologist's exam couldn't detect because they we're never looking inside.

Skin problems | Nepute Wellness
Topical steroids thin skin over time and suppress the immune signal without resolving it
Topical steroids thin skin over time and suppress the immune signal without resolving it
Skin problems | Nepute Wellness
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Gut permeability and dysbiosis are connected to eczema, psoriasis, and acne
Skin problems | Nepute Wellness
Food sensitivities trigger inflammatory skin reactions that topicals cannot address
Food sensitivities trigger inflammatory skin reactions that topicals cannot address
YOUR QUESTIONS ANSWERED

Common Questions About Skin Problems and Internal Health

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.