Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

Understanding Hypertension

What is actually causing your high blood pressure?

Nearly half of American adults have hypertension. Most are given medication and told to cut salt from their diet, but given no explanation for why their blood pressure is high in the first place. The root cause can range from insulin resistance to hormonal imbalance to mineral deficiency, and most people are never tested for any of them.
High blood pressure | Nepute Wellness
BEYOND THE NUMBERS

More Medications Won't Answer the Question Your Doctor Never Asked

One medication becomes two. Two becomes three. Blood pressure still isn't well controlled, and each new drug adds its own side effects — fatigue, dizziness, brain fog, muscle cramps. Meanwhile the underlying root cause goes uninvestigated. Standard hypertension care monitors numbers and adjusts dosages. It rarely asks why the pressure is high in the first place.
Your Nervous System Can Keep Blood Pressure Elevated Even When Everything Else Looks Normal
Most Hypertension Patients Have Never Had Their Insulin Levels Tested
Magnesium Deficiency Has A Direct Effect On Blood Pressure And Is Rarely Part Of Any Standard Workup

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Organ & Artery Ultrasound
Electrocardiogram (EKG)
Nutritional Counseling
Comprehensive Blood Panels
Understanding Hypertension

The Number on the Cuff Is the Result, Not the Cause.

High blood pressure does not have one root cause. Several distinct biological pathways can all produce elevated pressure, and they require different responses. Understanding which one applies to you is the first step toward addressing it.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

Insulin Resistance

Chronically elevated insulin signals the kidneys to retain sodium, increases blood volume, activates the sympathetic nervous system, and gradually stiffens arterial walls. All of which raise blood pressure independent of salt intake.

Magnesium & Mineral Deficiency

Magnesium relaxes smooth muscle tissue including the walls of your arteries. Potassium helps your kidneys excrete excess sodium. Deficiencies in either, both extremely common, directly affect how your body regulates pressure.

Autonomic Dysfunction

Your autonomic nervous system regulates heart rate and vascular tone. When the sympathetic (stress) side stays chronically dominant, vessels remain constricted and pressure stays elevated even during rest.

Hormonal Imbalance

Cortisol, aldosterone, and thyroid hormones each play a direct role in blood pressure regulation. An imbalance in any one of them can sustain elevated pressure even when other markers appear normal.

Vascular Inflammation

Chronic inflammation damages the endothelial lining of blood vessels, reducing their ability to dilate properly and increasing vascular resistance. A measurable and frequently overlooked root cause.

Toxic Load

Exposure to heavy metals including lead and cadmium has been directly linked to hypertension in peer-reviewed research. Environmental contributors are rarely assessed in standard care but are testable and when present, addressable.

THE SILENT COST OF INACTION

Hypertension Damages More Than Your Heart.

Understanding Stress and Your Body
Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.
The Functional Medicine Difference

A Lifetime of Pills Isn't a Plan...

If the only conversations about your blood pressure have involved which medication to add next, you are managing a number, not addressing a cause. And if you have never had comprehensive testing to identify the root cause of your hypertension, it is time to find out why. At Nepute Wellness, that is exactly where every patient journey begins.
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Beyond Managing a Number

High Blood Pressure Does Not Have to Be a Lifetime Sentence.

Understanding what is actually driving it opens the door to outcomes that medication alone rarely delivers.

Reduced Medication Dependence

When the root cause is identified and addressed, many people are able to reduce or eliminate blood pressure medications under physician supervision.

A Quieter Nervous System

Many root causes of hypertension keep the body in a chronic stress state. Resolving them often brings improvements in sleep, anxiety, and daily energy that go well beyond blood pressure.

Long Term Protection

High blood pressure silently damages the brain, kidneys, and cardiovascular system over time. Addressing the root cause early is one of the most protective health decisions a person can make.

Whole Body Impact

Most root causes of hypertension affect multiple body systems simultaneously. When those are resolved, improvements across energy, cognition, and metabolic health frequently follow.
Related Testing & Treatments
Ultrasound artery | Nepute Wellness

Organ & Artery Ultrasound

NON-INVASIVE DIAGNOSTIC IMAGING

Stress resilience testing | Nepute Wellness

Electrocardiogram (EKG)

CARDIAC HEALTH SCREENING

Nutrition help | Nepute Wellness

Nutritional Counseling

PERSONALIZED THERAPEUTIC NUTRITION

Blood panel | Nepute Wellness

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

REAL PATIENT EXPERIENCES

Nepute Wellness Reviews

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My family has been going here for years and are thankful for everyone there. Dr. Nepute stands by his oath in caring for people no matter your issue instead of putting a bandaid on it. I find the reviews funny that condemn him for recommending supplements yet have no problem with doctors prescribing medicines that cause side effects so they can add another medicine for that side effect! Exactly what big pharm want.all of us drugged up for life. I trust Dr. Nepute and am thankful to have found him.
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Cindy Cline
Google Review
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Doc and his staff have completely changed my life. I have been suffering from chronic pain and inflamation. I have been going there for several years now. Dr. Eric, Dr. Rachel, Dr. Patric and staff have been extremely helpful. I have learned how to stay healthy and how to heal. I am in my sixties and very active. I plan on staying that way with the help of Nepute wellness. Over the years I have used traditional medicine only to be given pills that mask the pain. Neputi wellness has given me a holistic path to getting heathy and staying well. This type of wellness takes time. Have patience. You will be amazed ! Update 8/1/25 I just wanted to share that I have been taking the biolimitlist Neuro Reboot. My chronic pain has decreased to almost nothing. Especially in my lower back. This has allowed me to live the active life that I am accustomed to. I have been trying to avoid medications at all costs but was starting to give in. This product is working well. In my case, it took almost 60 days. But from then on, it was amazing. I noticed the first week I was sleeping better. The pain in my joints was starting to ease. My back, however, took a longer time. In my opinion, it is worth the money. And many thanks to doc and his amazing staff!
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Tony Frisella
Google Review
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I Always leave feeling great
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Thomas Smith
Google Review
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I look forward to my weekly appointments! With the help of Dr Nepute and other Doctors in his office, I know longer take medication. I was on diabetic meds, high blood pressure and cholesterol. I now just take supplements. His restart program is amazing! I’ve dropped over 100lbs! I recommend him to all of my family and friends!
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elisabeth peeples
Google Review
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Everyone there is awesome. John and Mike know how to work on my neck and I have had neck problems my whole life. I feel better everutime I leave. Can’t recommend enough.
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Peter P
Google Review
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The best wellness center around St louis
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Dhrutika Patel
Google Review
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This place is AMAZING ! They actually fix your problems instead of putting bandaids on them . It has truly helped me feel so much better. The doctors are very thorough and take time with you . The nurses and staff are super helpful and ALWAYS friendly ! I highly recommend it !
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Lynn Brock
Google Review
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People are always so polite and helpful. Making you feel comfortable your entire visit. Lots of smiles.
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Kelley Kull
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Dr Nepute and his staff, are ALL professional, courteous and personable.
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Ray Lewis
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I would highly recommend Nepute wellness to anyone . No matter what your health issue is the staff and doctors are ready to help , have been going for years and will continue to go for many years to come . Great job !
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Linda Anthony
Google Review
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I have never felt more comfortable and confident that my needs were being addressed courteously, confidentially and professionally. Best staff of caring technicians ever. They address the cause and you get educated to the point where you actually understand. Was just there a few days ago. My nurse Tanya and all are a notch above any experience I have ever had. Lov Nepute Wellness
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John Kinnison aka 'Kinno'
Google Review
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Very good service and care. Highly recommend Nepute Wellness!
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Jean Schlueter
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Very informative. They know their craft.
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Ina Betts
Google Review
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A place where the doctors care about your true health and help you fix it naturally! Always been nothing but pleased when going here. They work with you on everything to make sure you are healthy and don’t neglect yourself because of money or time. My son did a brain balance program there (no longer there though) and it helped him tremendously. Chiropractic care helps with any issue you may have! They always have the newest technology or therapy (like the laser that I recently used after a car accident I had) to help you be out of pain. I have carpal tunnel and regular adjustments keep my hand from falling asleep at night. pain goes away also. Highly recommend!
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Lisa Siebel
Google Review
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Excellent service, diligent care and courteous workers. They make you feel at home here.
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José Jacinto
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HOW WE INVESTIGATE HYPERTENSION

Beyond the Cuff: A Different Approach to Blood Pressure

We begin with comprehensive blood panels measuring fasting insulin, inflammatory markers, mineral status, and metabolic function. Combined with cardiovascular testing like EKG and HRV analysis, we build a complete picture of what's actually driving your blood pressure.

High blood pressure | Nepute Wellness
Your Nervous System Can Keep Blood Pressure Elevated Even When Everything Else Looks Normal
Your Nervous System Can Keep Blood Pressure Elevated Even When Everything Else Looks Normal
High blood pressure | Nepute Wellness
Most Hypertension Patients Have Never Had Their Insulin Levels Tested
Most Hypertension Patients Have Never Had Their Insulin Levels Tested
High blood pressure | Nepute Wellness
Magnesium Deficiency Has A Direct Effect On Blood Pressure And Is Rarely Part Of Any Standard Workup
Magnesium Deficiency Has A Direct Effect On Blood Pressure And Is Rarely Part Of Any Standard Workup
YOUR QUESTIONS ANSWERED

Nepute Wellness FAQs

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.