Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

METABOLIC DYSFUNCTION IS REVERSIBLE

Your Blood Sugar Problems Started Years Before Your Lab Flagged Them

The crashes, the cravings, the brain fog after meals. You may have been told your glucose is “borderline” or to “watch your diet.” But insulin resistance begins a decade before
Blood sugar issues | Nepute Wellness
THE METABOLIC BLIND SPOT

Standard Blood Work Misses the Problem Until It's Advanced

Your annual physical checks fasting glucose. If it's under 100, you're told everything is fine. But fasting insulin -- the early warning marker that reveals metabolic dysfunction years before glucose rises -- is almost never tested. By the time glucose is elevated, your pancreas has been overproducing insulin for years.
Fasting glucose is a late marker -- insulin resistance develops 8 to 10 years earlier
Energy crashes and cravings signal metabolic dysfunction the lab won't flag yet
Insulin resistance drives weight gain, inflammation, and cardiovascular risk

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Nutritional Counseling
Hormone Testing
Comprehensive Blood Panels
DNA Discovery Test
THE INSULIN STORY

Why Your Body Struggles to Handle Sugar Like It Used To

Insulin is the hormone that moves glucose out of your blood and into your cells for energy. When cells become resistant to insulin's signal, your pancreas produces more and more to compensate. This silent escalation drives weight gain, inflammation, fatigue, and cravings long before blood sugar rises.
— FEATURED RESOURCE —
Health Guides & Protocols

Personal Health Inventory: What Matters to You

A self-assessment tool from the VA Whole Health program that helps you identify what matters most and create a personalized path to wellness.

Each time you eat, insulin rises to move glucose into cells. When cells resist the signal, the pancreas pushes harder.

Elevated insulin triggers systemic inflammation through multiple pathways. This inflammation further damages insulin receptors, creating a vicious cycle of worsening blood sugar control. Breaking this cycle requires addressing both the metabolic and inflammatory components.

A comprehensive metabolic evaluation measures fasting insulin, HbA1c, fasting glucose, triglyceride-to-HDL ratio, and inflammatory markers together.

THE PROGRESSION NOBODY WARNED YOU ABOUT

Insulin Resistance Doesn't Stay a Blood Sugar Problem

Personal Health Inventory: What Matters to You
A self-assessment tool from the VA Whole Health program that helps you identify what matters most and create a personalized path to wellness.
SELFCARE AS HEALTHCARE

You Have More Control Over Your Metabolism Than You've Been Told

Prediabetes is not a waiting room for diabetes. It's a signal that your metabolism needs support now -- not in five years when your glucose finally crosses a threshold. Identifying insulin resistance early and intervening with targeted nutrition, testing, and lifestyle changes is Selfcare.
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METABOLIC FREEDOM

Imagine Your Blood Sugar Working Properly

Picture steady energy between meals, no desperate afternoon crashes, and waking up with blood sugar that has stabilized through the night — your metabolism finally working in rhythm instead of against you.

Stable Energy

Energy that may stay steadier throughout the day - reduced crashes and cravings.

Freedom from Cravings

Cravings often diminish as your body learns to use fuel more efficiently.

True Satisfaction

Feel more satisfied after meals without constantly thinking about food.

Weight Response

Your body may start responding better to your efforts.

Clear Thinking

Brain fog often lifts when metabolic function improves.

Protected Future

Take proactive steps toward healthier metabolic function. Individual results may vary.
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Nutritional Counseling

PERSONALIZED THERAPEUTIC NUTRITION

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Hormone Testing

COMPREHENSIVE HORMONE ASSESSMENT

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Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

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DNA Discovery Test

PERSONALIZED GENETIC INTELLIGENCE

REAL PATIENT EXPERIENCES

People Who Took Back Control of Their Metabolism

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I have had problems with digestion for years. I am a healthy 62 year old Dental Hygienist and live a healthy active life. However my stomach issues have been there for years. Being a healthcare provider, I’m always cautious and leery of claims of boosting health energy etc. That was until I started following Dr Napute’s and vice, and watching his videos, I finally got the Digestive Enzymes and Warrior Water! Oh my goodness! These 2 products have changed my life and stomach forever! Almost completely eliminated my heartburn and night time acid reflux, I feel better, more energy, sleep better, the list goes on! I will never go a day without these 2 products! Thank you Dr Napute! Just so you know, I often tell my dental hygiene patients about you! Thank you Dr.! God bless you for spreading the news about these great products and educating us about healthy choices! Blessings, Lisa B. San Diego CA
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Lisa B
Google Review
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Fast friendly and easy
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Audrey Hamper
Google Review
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Dr. Nepute and his team deliver a truly exceptional level of care that stands far above the rest. The advanced, results-driven approach they take is both comprehensive and refreshingly effective. Every aspect of the patient experience – from the in-depth consultations to the clear, consistent communication – is handled with an impressive attention to detail. What sets Dr. Nepute apart is not only his deep clinical expertise, but also his commitment to patient education and empowerment. You leave feeling informed, supported, and genuinely cared for. This is integrative care at its finest!
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Mary Lynn Papin
Google Review
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Doctor Nepute is proactive and when we couldn’t figure something out he referred me and it was helpful with my diagnosis. Dr Rachel is amazing at finding the right places to adjust and what to recommend for continuing care. The support staff is amazing and are always willing to get answers for you. Thank you so much.
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Colleen Cofer
Google Review
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Getting healthy!
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Pam Gonzalez
Google Review
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The staff here are wonderful and patient! I always receive excellent care. I drove nearly 3 hours, one way, because of what they have to offer. I’ve been a patient for approximately 4 years.
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Greta Howard
Google Review
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Very friendly. Wonderful staff. I always walk out feeling better
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Jan Puscian
Google Review
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Has helped my back and overall health tremendously
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Sandra Lynch
Google Review
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Always friendly and take their time with my needs. Very helpful in answering my questions and work to educate me on how I can take command of my own health.
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Bethany Kjellesvik
Google Review
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A place where the doctors care about your true health and help you fix it naturally! Always been nothing but pleased when going here. They work with you on everything to make sure you are healthy and don’t neglect yourself because of money or time. My son did a brain balance program there (no longer there though) and it helped him tremendously. Chiropractic care helps with any issue you may have! They always have the newest technology or therapy (like the laser that I recently used after a car accident I had) to help you be out of pain. I have carpal tunnel and regular adjustments keep my hand from falling asleep at night. pain goes away also. Highly recommend!
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Lisa Siebel
Google Review
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My experience at my initial appointment was amazing! The office process ran smoothly, they explained everything including pricing, the medical assistant doing all of my testing was compassionate and kind And answered all of my questions, and the doctor that did my chiropractic adjustment provided me with some great insights about my x-rays as well as about the adjustment she was doing. I left feeling no pain in my neck And hopeful that we will get to the bottom of my symptoms.
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Gina Prinzavalli
Google Review
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The staff, as well as the doctors here are extremely helpful. Family oriented environment. Very knowledgeable, and fully equipped to address just about any ailments. I highly recommend Nepute Wellness as your caregiver.
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Herschel Turner
Google Review
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Kind, caring, informative, and detailed in treatment not leaving a person more confused about what to do next.it’s a nice change from what I’m used to.
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Danielle Campbell
Google Review
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Among the best in STL. Dr. Nepute helps address the “cause” not the symptom. Highly recommended!
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Barry Clifton
Google Review
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Staff is friendly and very helpful. Dr’s are very knowledgeable, they listen and show that they care. Highly recommend!
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Rhonda Lamb
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HOW WE ASSESS METABOLIC HEALTH

Comprehensive Testing That Catches What Standard Labs Miss

We measure fasting insulin alongside glucose, HbA1c, lipid ratios, and inflammatory markers — building a metabolic picture that starts years before diabetes shows up on a standard test. Most doctors check glucose alone. We check the entire pathway.

Blood sugar issues | Nepute Wellness
Fasting glucose is a late marker -- insulin resistance develops 8 to 10 years earlier
Fasting glucose is a late marker -- insulin resistance develops 8 to 10 years earlier
Blood sugar issues | Nepute Wellness
Energy crashes and cravings signal metabolic dysfunction the lab won't flag yet
Energy crashes and cravings signal metabolic dysfunction the lab won't flag yet
Blood sugar issues | Nepute Wellness
Insulin resistance drives weight gain, inflammation, and cardiovascular risk
Insulin resistance drives weight gain, inflammation, and cardiovascular risk
YOUR QUESTIONS ANSWERED

Common Questions About Blood Sugar and Metabolism

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.