Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

YOUR STRESS RESPONSE IS RUNNING

Adrenal Fatigue Is Your Body Telling You the Tank Is Empty

Exhausted but wired. Crashing every afternoon. Relying on caffeine to function and still falling short. A single morning cortisol test will not reveal what is wrong. Comprehensive testing will.
Adrenal fatigue | Nepute Wellness
WHY COFFEE STOPPED WORKING

Your Cortisol Rhythm Is Broken and Nobody Has Measured It

You used to handle stress. Now everything feels like too much. You crash after lunch, cannot fall asleep at night, and rise feeling like you never rested. Your doctor checked your cortisol once, at 8 a.m., and said it was normal. But cortisol follows a rhythm throughout the day.
A single morning cortisol test misses the daily rhythm that matters most
Caffeine masks the problem while further taxing depleted adrenals
Chronic HPA axis dysfunction affects hormones, immunity, and metabolism

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Stress Resilience Evaluation
Hormone Testing
Comprehensive Blood Panels
Heart Rate Variability (HRV) Testing
THE HPA AXIS EXPLAINED

Why Your Stress System Controls More Than You Realize

The hypothalamic-pituitary-adrenal axis is your central stress regulation system. It governs cortisol production, energy distribution, immune response, and sleep cycles. When this axis is dysregulated, the effects cascade through every major body system.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

Healthy cortisol peaks in the morning and declines through the day. HPA dysfunction can flatten, invert, or spike this rhythm unpredictably.

When your body prioritizes cortisol production under chronic stress, it diverts resources from thyroid, sex hormone, and immune function.

Prolonged HPA activation eventually leads to blunted output: the adrenals can no longer respond adequately, leaving you depleted and vulnerable.

WHEN ADRENAL DYSFUNCTION IS IGNORED

Running on Empty Does Not Build Resilience, It Erodes It

Understanding Stress and Your Body
Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.
TEST, DON'T GUESS

A Four-Point Cortisol Map Reveals What One Lab Draw Cannot

If nobody has measured your cortisol at multiple points throughout the day, you have not been tested for adrenal dysfunction. You have been screened and missed. Our philosophy is Test, Don't Guess. We map your cortisol rhythm, assess DHEA levels, and explorevaluate the full HPA axis response.
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ENERGY RESTORED

Imagine Having Your Energy Back

Picture waking up rested and ready instead of exhausted before your feet hit the floor — your energy consistent through the day, your body no longer running on fumes from adrenal reserves it cannot replenish.

Sustained Energy

Energy that lasts throughout the day without crashes.

Stable Days

Days without the exhaustion roller coaster.

Stress Capacity

Handle stress without being overwhelmed or depleted.

Restful Sleep

Fall asleep easily and wake refreshed. This improvement is supported by identifying and addressing underlying root causes with a personalized care plan.

Resilience Returns

Feel resilient again - able to handle what life throws at you.

Clear Understanding

Know exactly what's wrong with your stress response and how you're fixing it.
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Stress Resilience Evaluation

COMPREHENSIVE STRESS RESPONSE TESTING

Hormone testing | Nepute Wellness

Hormone Testing

COMPREHENSIVE HORMONE ASSESSMENT

Blood panel | Nepute Wellness

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

Stress resilience testing | Nepute Wellness

Heart Rate Variability (HRV) Testing

AUTONOMIC NERVOUS SYSTEM ASSESSMENT

PATIENT EXPERIENCES

What Patients Say About Adrenal Recovery at Nepute Wellness

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Great doctor who will show you the best way to be healthy.
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Roseanna Hottel
Google Review
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Dr Nepute is amazing, so knowledgeable, and his team of professionals are so eager to help in any way! I feel blessed to get connected and have hope for my health to vastly improve!
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Vicky Abner
Google Review
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The best wellness center around St louis
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Dhrutika Patel
Google Review
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This place is a warm & friendly atmosphere that helps relieve pain with various treatments & gets to the root cause of your pain by addressing that to help defend against future physical problems.
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Leslie Gonzalez
Google Review
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Went to Nepute Wellness this afternoon & did I feel great walking out of there. I’ve been getting adjustments & treatment for 10 plus years & what a game changer it’s been. I get Meyer Cocktaiks & B12 shots twice a month. Dr. Eric is the best
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Patti Conger
Google Review
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Very nice Nurses and doctors, ran all my test for low price and multivitamin Intravenous worked really good taking away my foot pain.
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George Smith
Google Review
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Nice place to go and nice place to be.
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Jack Cox
Google Review
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It was so amazing!
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Chloe Smith
Google Review
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I had been in pain for weeks. I tried everything that I could think of to get relief including a trip to the er. My husband suggested that we go to Nepute Wellness (as we had been clients before) and with just one adjustment I am feeling much better. I trust the staff at Nepute Wellness and will continue to go back.
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Saundra Olson
Google Review
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I am so overly impressed with Dr. Nepute, the staff, and the care they have given me. I fly in from Texas to specifically be treated by Nepute Wellness center. They discovered issues that had been missed and overlook by mainstream doctors for years that were all treatable through diet and non-harmful supplements, unlike most doctors who want to push harmful pharmaceuticals. Their staff is friendly, caring, and compassionate! I highly recommend Nepute Wellness to anyone, especially those who have struggled with health issues that have been unresolved by mainstream doctors and meds! Thanks Dr Nepute and Staff!
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Andy
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Dr. Nepute and his team deliver a truly exceptional level of care that stands far above the rest. The advanced, results-driven approach they take is both comprehensive and refreshingly effective. Every aspect of the patient experience – from the in-depth consultations to the clear, consistent communication – is handled with an impressive attention to detail. What sets Dr. Nepute apart is not only his deep clinical expertise, but also his commitment to patient education and empowerment. You leave feeling informed, supported, and genuinely cared for. This is integrative care at its finest!
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Mary Lynn Papin
Google Review
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Dr. Nepute is an amazing chiropractor who cares about your health. He isn’t about masking the problem, he’s about fixing the problem.
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Eagles Landing Subdivision
Google Review
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They are all wonderful
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Shonna Morrison
Google Review
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My family and I love going to Nepute Wellness. The staff is very friendly and the Doctor’s really do care about our health.
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Jenn Lewis
Google Review
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Great people that work at Wellness Center! What more can I say? They are awesome!❤️
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Kent Ohlendorf
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HOW WE MAP YOUR STRESS

Multi-Point Cortisol Testing and Full HPA Axis Evaluation

Your adrenal assessment uses four-point cortisol testing throughout the day, DHEA levels, comprehensive hormone panels, blood sugar patterns, and inflammatory markers. We are measuring how depleted your reserves actually are — not guessing from symptoms alone.

Adrenal fatigue | Nepute Wellness
A single morning cortisol test misses the daily rhythm that matters most
A single morning cortisol test misses the daily rhythm that matters most
Adrenal fatigue | Nepute Wellness
Caffeine masks the problem while further taxing depleted adrenals
Caffeine masks the problem while further taxing depleted adrenals
Adrenal fatigue | Nepute Wellness
Chronic HPA axis dysfunction affects hormones, immunity, and metabolism
Chronic HPA axis dysfunction affects hormones, immunity, and metabolism
COMMON QUESTIONS

Frequently Asked Questions About Adrenal Fatigue

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.