YOUR STRESS RESPONSE IS RUNNING

Adrenal Fatigue Is Your Body Telling You the Tank Is Empty

Exhausted but wired. Crashing every afternoon. Relying on caffeine to function and still falling short. A single morning cortisol test will not reveal what is wrong. Comprehensive testing will.

WHY COFFEE STOPPED WORKING

Your Cortisol Rhythm Is Broken and Nobody Has Measured It

You used to handle stress. Now everything feels like too much. You crash after lunch, cannot fall asleep at night, and rise feeling like you never rested. Your doctor checked your cortisol once, at 8 a.m., and said it was normal. But cortisol follows a rhythm throughout the day.

A single morning cortisol test misses the daily rhythm that matters most

Caffeine masks the problem while further taxing depleted adrenals

Chronic HPA axis dysfunction affects hormones, immunity, and metabolism

Helpful Links

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Stress Resilience Evaluation

Hormone Testing

Comprehensive Blood Panels

Heart Rate Variability (HRV) Testing

THE HPA AXIS EXPLAINED

Why Your Stress System Controls More Than You Realize

The hypothalamic-pituitary-adrenal axis is your central stress regulation system. It governs cortisol production, energy distribution, immune response, and sleep cycles. When this axis is dysregulated, the effects cascade through every major body system.

— FEATURED RESOURCE —

Health Guides & Protocols

Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

Healthy cortisol peaks in the morning and declines through the day. HPA dysfunction can flatten, invert, or spike this rhythm unpredictably.

When your body prioritizes cortisol production under chronic stress, it diverts resources from thyroid, sex hormone, and immune function.

Prolonged HPA activation eventually leads to blunted output: the adrenals can no longer respond adequately, leaving you depleted and vulnerable.

WHEN ADRENAL DYSFUNCTION IS IGNORED

Running on Empty Does Not Build Resilience, It Erodes It

Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

TEST, DON'T GUESS

A Four-Point Cortisol Map Reveals What One Lab Draw Cannot

If nobody has measured your cortisol at multiple points throughout the day, you have not been tested for adrenal dysfunction. You have been screened and missed. Our philosophy is Test, Don't Guess. We map your cortisol rhythm, assess DHEA levels, and explorevaluate the full HPA axis response.

ENERGY RESTORED

Imagine Having Your Energy Back

Picture waking up rested and ready instead of exhausted before your feet hit the floor — your energy consistent through the day, your body no longer running on fumes from adrenal reserves it cannot replenish.

Sustained Energy

Energy that lasts throughout the day without crashes.

Stable Days

Days without the exhaustion roller coaster.

Stress Capacity

Handle stress without being overwhelmed or depleted.

Restful Sleep

Fall asleep easily and wake refreshed. This improvement is supported by identifying and addressing underlying root causes with a personalized care plan.

Resilience Returns

Feel resilient again - able to handle what life throws at you.

Clear Understanding

Know exactly what's wrong with your stress response and how you're fixing it.

Stress Resilience Evaluation

COMPREHENSIVE STRESS RESPONSE TESTING

Hormone Testing

COMPREHENSIVE HORMONE ASSESSMENT

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

Heart Rate Variability (HRV) Testing

AUTONOMIC NERVOUS SYSTEM ASSESSMENT

PATIENT EXPERIENCES

What Patients Say About Adrenal Recovery at Nepute Wellness

The staff was so professional and organized. There was no long wait time and Dr. Nepute was very focused on the best way to get me well again.

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Jeannie Holder

Google Review

I appreciate so much the wisdom and knowledge Dr. Patrick accessed my test results and relayed to me over the phone. We live to far away to run back and forth to the office. Thank you for helping me

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Patricia Duncan

Google Review

Napute Wellness is an efficient and informational CHIROPRACTIC practice. All the staff were professional and helpful. This is the place to be for chiropractic treatment in St. Louis!

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Phyllis Gonzalez

Google Review

Great facility and caring providers. Look forward to going there for my visits.

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Tracy Jaycox

Google Review

My experience is overwhelmingly positive. The treatment I received has improved my condition. I am experiencing much less pain and have regained mobility in 2 visits for a very bad sciatica issue. D

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Ervịna. D

Google Review

Went in for severe back pain and Dr Eric and his amazing staff at Nepute wellness were able to correct the issue in just two quick visits! Truly a remarkable place with top notch staff. Very very highly recommend! -Aaron r.

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Libby Hillemeyer

Google Review

I can’t express how MUCH Nepute Wellness Center has helped me with an onset of arthritis! ALL the treatments have helped tremendously to relieve the pain and discomfort – when I first went there, I couldn’t even stand straight up! Now, I can move about normally. I cannot say enough about all the great people there who are so pleasant and show how much they care about HOW you’re doing! And Dr. Nepute is so knowledgeable, so friendly, so concerned about what’s going on with you. I recommend Nepute Wellness to anyone who does NOT want ‘cookie-cutter’ treatment, but is looking for top-of-the-line care for their health concern by people ‘who REALLY CARE’!

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bobbi s

Google Review

My experience at my initial appointment was amazing! The office process ran smoothly, they explained everything including pricing, the medical assistant doing all of my testing was compassionate and kind And answered all of my questions, and the doctor that did my chiropractic adjustment provided me with some great insights about my x-rays as well as about the adjustment she was doing. I left feeling no pain in my neck And hopeful that we will get to the bottom of my symptoms.

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Gina Prinzavalli

Google Review

Nepute wellness Center is by far the best care I’ve experienced after being blessed to have had the best medical care from two different hospitals, and several injuries! I have been in the hospital 2 times in my life for a year both times. I’ve had multiple broken bones, struck by lightning. Several years later I was electrocuted by7200 volts, while working on a radio tower and a 40 ft fall. I’ve had several people who have known me speak that I am as tough as they come! But I tell you it’s the Grace of God who has brought me through these trials, moreover, to Nepute Wellness Center. My body has dealt with pain and arthritis for decades, and I am without a doubt a man of faith, and I have already seen results in a short amount of time. I have been blessed to find a entire group of people who care about people more than the bottom line. Pastor Jerry T.McClain

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Jerry McClain

Google Review

Always feel much better after leaving this office. The team does a great job with helping relieve pain and getting me back to living.

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David Hoft

Google Review

Among the best in STL. Dr. Nepute helps address the “cause” not the symptom. Highly recommended!

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Barry Clifton

Google Review

100% the most caring chiropractors with top notch service. I have yet to see anyone coming into the office and not treated like VIPs!

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Robbie Houston

Google Review

Friendly staff, Nepute Wellness keeps me going to do the things I want to do. Thanks to ALL of YOU

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Diane Hotard

Google Review

Awesome staff. They have helped me turn my health around. I am down from 6 prescriptions to just 1. Feeling great!

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Judith Caves

Google Review

All the workers take excellent care of the patients.

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James Christian

Google Review

HOW WE MAP YOUR STRESS

Multi-Point Cortisol Testing and Full HPA Axis Evaluation

Your adrenal assessment uses four-point cortisol testing throughout the day, DHEA levels, comprehensive hormone panels, blood sugar patterns, and inflammatory markers. We are measuring how depleted your reserves actually are — not guessing from symptoms alone.

A single morning cortisol test misses the daily rhythm that matters most

Caffeine masks the problem while further taxing depleted adrenals

Chronic HPA axis dysfunction affects hormones, immunity, and metabolism

COMMON QUESTIONS

Frequently Asked Questions About Adrenal Fatigue

What is the Seven Stages of Disconnection?

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Can international patients visit Nepute Wellness?

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

Do I need a referral to visit Nepute Wellness?

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

What should I expect during my first visit to Nepute Wellness?

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

What BioLimitless supplements are recommended at Nepute Wellness?

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

What is the refund and cancellation policy?

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

What are the virtual appointment options and how long are they?

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

15-Minute Quick Hit ($42): Focused check-in or targeted question session
30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

What does 'Selfcare as Healthcare' mean?

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

What is the Health Investment Plan?

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

What does 'blocked, not broken' mean at Nepute Wellness?

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:

Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.

Connect From Anywhere

Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.

Cell Signals, Detox Pro Plus & Master Microbiotics

Detox, gut health, and cellular communication. The three pillars of foundational wellness.

Ready to Discover The Root Cause of Your Symptoms?

Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.

Unlock Your Genetic Blueprint

Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.

Direct Nutrients, Maximum Absorption

You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.