Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

YOUR STRESS RESPONSE IS RUNNING

Adrenal Fatigue Is Your Body Telling You the Tank Is Empty

Exhausted but wired. Crashing every afternoon. Relying on caffeine to function and still falling short. A single morning cortisol test will not reveal what is wrong. Comprehensive testing will.
Adrenal fatigue | Nepute Wellness
WHY COFFEE STOPPED WORKING

Your Cortisol Rhythm Is Broken and Nobody Has Measured It

You used to handle stress. Now everything feels like too much. You crash after lunch, cannot fall asleep at night, and rise feeling like you never rested. Your doctor checked your cortisol once, at 8 a.m., and said it was normal. But cortisol follows a rhythm throughout the day.
A single morning cortisol test misses the daily rhythm that matters most
Caffeine masks the problem while further taxing depleted adrenals
Chronic HPA axis dysfunction affects hormones, immunity, and metabolism

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Book a Virtual Consultation with Dr. Nepute!

Explore Potential Treatments

Stress Resilience Evaluation
Hormone Testing
Comprehensive Blood Panels
Heart Rate Variability (HRV) Testing
THE HPA AXIS EXPLAINED

Why Your Stress System Controls More Than You Realize

The hypothalamic-pituitary-adrenal axis is your central stress regulation system. It governs cortisol production, energy distribution, immune response, and sleep cycles. When this axis is dysregulated, the effects cascade through every major body system.
— FEATURED RESOURCE —
Health Guides & Protocols

Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

Healthy cortisol peaks in the morning and declines through the day. HPA dysfunction can flatten, invert, or spike this rhythm unpredictably.

When your body prioritizes cortisol production under chronic stress, it diverts resources from thyroid, sex hormone, and immune function.

Prolonged HPA activation eventually leads to blunted output: the adrenals can no longer respond adequately, leaving you depleted and vulnerable.

WHEN ADRENAL DYSFUNCTION IS IGNORED

Running on Empty Does Not Build Resilience, It Erodes It

Understanding Stress and Your Body
Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.
TEST, DON'T GUESS

A Four-Point Cortisol Map Reveals What One Lab Draw Cannot

If nobody has measured your cortisol at multiple points throughout the day, you have not been tested for adrenal dysfunction. You have been screened and missed. Our philosophy is Test, Don't Guess. We map your cortisol rhythm, assess DHEA levels, and explorevaluate the full HPA axis response.
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ENERGY RESTORED

Imagine Having Your Energy Back

Picture waking up rested and ready instead of exhausted before your feet hit the floor — your energy consistent through the day, your body no longer running on fumes from adrenal reserves it cannot replenish.

Sustained Energy

Energy that lasts throughout the day without crashes.

Stable Days

Days without the exhaustion roller coaster.

Stress Capacity

Handle stress without being overwhelmed or depleted.

Restful Sleep

Fall asleep easily and wake refreshed. This improvement is supported by identifying and addressing underlying root causes with a personalized care plan.

Resilience Returns

Feel resilient again - able to handle what life throws at you.

Clear Understanding

Know exactly what's wrong with your stress response and how you're fixing it.
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Stress Resilience Evaluation

COMPREHENSIVE STRESS RESPONSE TESTING

Hormone testing | Nepute Wellness

Hormone Testing

COMPREHENSIVE HORMONE ASSESSMENT

Blood panel | Nepute Wellness

Comprehensive Blood Panels

ADVANCED DIAGNOSTIC BLOOD CHEMISTRY

Stress resilience testing | Nepute Wellness

Heart Rate Variability (HRV) Testing

AUTONOMIC NERVOUS SYSTEM ASSESSMENT

PATIENT EXPERIENCES

What Patients Say About Adrenal Recovery at Nepute Wellness

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Dr Angelo is great!
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Joy Sauter
Google Review
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Dr. Nepute and his staff are AWESOME! Dr. Eric is very gifted in his profession and his heart are his patients. He only wants the best treatment for everyone in a way that God created us to have. His staff is so caring, welcoming and treats you like you are the only one there. They are a fine oiled machine that results in success. God has blessed their practice resulting in so many success stories, but He has also blessed me through divine intervention by placing these wonderful people in my life. I wish everyone can experience the type of God-given treatment we all deserve without having to deal with the bureaucracy of the world that is thrown at us every day of our lives. Thank you Dr. Eric and staff for all you do!
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Lisa Noerper
Google Review
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My experience at my initial appointment was amazing! The office process ran smoothly, they explained everything including pricing, the medical assistant doing all of my testing was compassionate and kind And answered all of my questions, and the doctor that did my chiropractic adjustment provided me with some great insights about my x-rays as well as about the adjustment she was doing. I left feeling no pain in my neck And hopeful that we will get to the bottom of my symptoms.
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Gina Prinzavalli
Google Review
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I don’t know where to start not only if I get into extreme new version of knowledge about my body but after setting up a long-term plan I’m already seeing results very early in the practice thank you guys so much
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William Duncan
Google Review
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Dr. E and the staff at Nepute Wellness have helped me and my family so much! Dr. E cares about his patients and truly listens! He wants to help heal instead of prescribing meds that just cover up the problem. My pain level has decreased, my health has improved and my quality of life is great! So thankful for this place!
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Lorrie Carpenter
Google Review
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I really don’t know where to start! This place is incredible! From the front desk, to the entire staff. Very knowledgeable, & friendly Dr’s. Chelsey, & Jacob have helped to restore my painful condition, & my health. Two of the best therapists I have ever seen. I feel like I have my life back again. I highly recommend Nepute Wellness to everyone. Thank you all.
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Christopher Artis
Google Review
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Was very impressed with the details and information and the time taken with me to show and talk to me about my health. I just wish the location was closer to me. Great team of people! Thanks!
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Marlo
Google Review
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I am so impressed with their facility and personalized level of care. The value they pack into one small but nice facility is impressive. It’s clear the primary focus is solely on providing the best care experience possible for the patient. I was amazed at everything they’re able to do in one day in one place fast tracking the road to healing. Dr Nepute is personable and caring with a vast knowledge of chronic diseases. He initiated a simple doable plan to help where others couldn’t. Because he and his staff are part of my health team I have hope of achieving a true level of wellness I thought was impossible. I encourage everyone especially skeptics and those who’ve been run around through the health care system for years to give this facility a try.
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Mandy Mason FSS
Google Review
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Looking forward to working with the team at Nepute Wellness. The initial visit for consultation and testing was a great experience, and they were extremely thorough in their interview process and in explaining their plans for dealing with issues.
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Judy Scheller
Google Review
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everyone was so nice and was very courteous when working with me
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gina loewenstein
Google Review
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The staff was very friendly, very professional, and answered all of my questions and concerns.
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Abdou Badjie
Google Review
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Amazing experience, everyone is so kind and inviting, they make sure you understand everything that is happening and why they do what they do. I had to get IV’s for my treatment and from someone who hates needles they did fantastic and made me super comfortable and relatively painless!
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Lydia Rose
Google Review
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Dr. Eric is the best! He truly takes the time to patiently teach us the right way to health. Layla is so good at what she does since while we were visiting I noticed she had already started my injection. Holly is always so pleasant and helpful. You all are a great team!
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Boyd Elliott
Google Review
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Great atmosphere Staff is super friendly, very knowledgeable and extremely accommodating. No matter how busy they are, you always receive one on one attention. Nepute’s Office is my Family’s primary care provider. 5 children from 18 all the way down to 3. Highly recommend a Dr’s office who absolutely does not help address you like a just another patient who believes that a pill or surgery may help support recovery from all. Believe it or not, our bodies do have the ability to heal themselves. We also actually have our own immune systems that fight against diseases. It’s just a matter of having a Dr who can assist in your personal direction to bring your body’s full potential to flourishing. I’m very happy my wife found Dr Nepute when she did.
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Scottie Kohlberg
Google Review
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This place has been a godsend. Two 1/2 years earlier I was a nightmare for everyone around me. Eric and his people have turned me around and I can’t wait to start my stem cells to get me fully back up and to a job. I love all of you at Nepute Wellness Center. You guys are amazing. Continue on the path for fighting for all of us Eric.
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chris Harper
Google Review
HOW WE MAP YOUR STRESS

Multi-Point Cortisol Testing and Full HPA Axis Evaluation

Your adrenal assessment uses four-point cortisol testing throughout the day, DHEA levels, comprehensive hormone panels, blood sugar patterns, and inflammatory markers. We are measuring how depleted your reserves actually are — not guessing from symptoms alone.

Adrenal fatigue | Nepute Wellness
A single morning cortisol test misses the daily rhythm that matters most
A single morning cortisol test misses the daily rhythm that matters most
Adrenal fatigue | Nepute Wellness
Caffeine masks the problem while further taxing depleted adrenals
Caffeine masks the problem while further taxing depleted adrenals
Adrenal fatigue | Nepute Wellness
Chronic HPA axis dysfunction affects hormones, immunity, and metabolism
Chronic HPA axis dysfunction affects hormones, immunity, and metabolism
COMMON QUESTIONS

Frequently Asked Questions About Adrenal Fatigue

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.