Office Phone: 314-544-5600

4225 Bayless Ave | St. Louis, MO 63123

SCIATICA AND RADIATING LEG PAIN

That Shooting Pain Down Your Leg Has a Source. Let's Find It.

The lightning bolt from your hip to your foot, the numbness that makes walking uncertain, the burning that no position relieves. Sciatica isn’t the problem. It’s the alarm.
Sciatica | Nepute Wellness
WHY SCIATICA KEEPS COMING BACK

Sciatica Isn't a Diagnosis. It's a Symptom of Something Deeper.

Most providers label your leg pain 'sciatica' and hand you a prescription. But sciatica just means your sciatic nerve is irritated. It doesn't explain WHY. A herniated disc, a misaligned vertebra, piriformis compression, or spinal stenosis all produce sciatic symptoms but require completely different approaches. Without identifying the specific mechanism, you could spend months on the wrong protocol.
Sciatica has at least five distinct causes that require different approaches to address
Nerve compression that persists may lead to permanent sensory or motor changes
Painkillers block the warning signal while the nerve remains under pressure

Have Questions?

Need help deciding what Product or Solution is a best fit for you? Ask BioLimitless A.I.

Explore Potential Treatments

X-Rays
Spinal Decompression Therapy
Physical Therapy
Chiropractic Care
Health Guides & Protocols

Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

Understanding Stress - Nepute Wellness Resource
Health Guides & Protocols

Personal Health Inventory: What Matters to You

A self-assessment tool from the VA Whole Health program that helps you identify what matters most and create a personalized path to wellness.

Personal Health Inventory - Nepute Wellness Resource
Health Guides & Protocols

Introduction to Whole Health: A Person-Centered Approach

This VA Whole Health guide introduces a person centered approach to wellness that aligns with root cause thinking and Selfcare as Healthcare.

VA Whole Health Intro - Nepute Wellness Resource
Health Guides & Protocols

The BioLimitless T.H.I.S. Framework: A Root Cause Approach

Explore the T.H.I.S. Framework: Triad of Health, Hierarchy of Health, Infinite Care System, and Seven Directives that guide the BioLimitless approach.

T.H.I.S. Framework - Nepute Wellness Resource
Cellular Health

Cellular Reset: The Tri-Peptide Metabolic Approach

Learn how Cellular Reset supports mitochondrial function, metabolic efficiency, and cellular energy through three advanced peptides working together.

Cr img | Nepute Wellness
Cell Signals Education

Cell Signals: The Science of Cellular Communication

Explore how Cell Signals supports cellular communication, energy production, and cognitive clarity through bioregulator technology and methylated nutrients.

Cs img | Nepute Wellness
Understanding Stress and Your Body

Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.

Personal Health Inventory: What Matters to You

A self-assessment tool from the VA Whole Health program that helps you identify what matters most and create a personalized path to wellness.

Introduction to Whole Health: A Person-Centered Approach

This VA Whole Health guide introduces a person centered approach to wellness that aligns with root cause thinking and Selfcare as Healthcare.

The BioLimitless T.H.I.S. Framework: A Root Cause Approach

Explore the T.H.I.S. Framework: Triad of Health, Hierarchy of Health, Infinite Care System, and Seven Directives that guide the BioLimitless approach.

Cellular Reset: The Tri-Peptide Metabolic Approach

Learn how Cellular Reset supports mitochondrial function, metabolic efficiency, and cellular energy through three advanced peptides working together.

Cell Signals: The Science of Cellular Communication

Explore how Cell Signals supports cellular communication, energy production, and cognitive clarity through bioregulator technology and methylated nutrients.

WHEN NERVE COMPRESSION PERSISTS

The Longer a Nerve Is Compressed, the Harder Recovery Becomes

Understanding Stress and Your Body
Research-based guidance on how stress affects your body and practical strategies for building stress resilience, from the National Institute of Mental Health.
Personal Health Inventory: What Matters to You
A self-assessment tool from the VA Whole Health program that helps you identify what matters most and create a personalized path to wellness.
Introduction to Whole Health: A Person-Centered Approach
This VA Whole Health guide introduces a person centered approach to wellness that aligns with root cause thinking and Selfcare as Healthcare.
The BioLimitless T.H.I.S. Framework: A Root Cause Approach
Explore the T.H.I.S. Framework: Triad of Health, Hierarchy of Health, Infinite Care System, and Seven Directives that guide the BioLimitless approach.
Cellular Reset: The Tri-Peptide Metabolic Approach
Learn how Cellular Reset supports mitochondrial function, metabolic efficiency, and cellular energy through three advanced peptides working together.
Cell Signals: The Science of Cellular Communication
Explore how Cell Signals supports cellular communication, energy production, and cognitive clarity through bioregulator technology and methylated nutrients.
YOU DESERVE A REAL DIAGNOSIS

Being Told 'It's Just Sciatica' Is Not an Answer

If the best your provider can offer is a label, a painkiller, and a referral to physical therapy that hasn't worked, you haven't received a diagnosis. You've received a description. Real answers require imaging, nerve function testing, and structural assessment that reveals exactly where and.
Dre | Nepute Wellness
Doclogobluewhite | Nepute Wellness
WHAT RECOVERY LOOKS LIKE

Imagine Life Without Sciatica Controlling Every Move

When the actual cause of sciatic nerve compression is addressed, not just the pain, patients often experience dramatic relief:

Walk Without Fear

Move freely without bracing for that shooting pain - walk, bend, and move with confidence.

Sit Comfortably Again

Sit through meals, meetings, and movies without the constant pain and numbness building.

Drive Without Dread

Road trips, commutes, and even short drives become possible again when nerve compression is resolved.

Sleep Through the Night

Wake up rested instead of exhausted from a night of shifting positions trying to escape the pain.

Avoid Surgery

The majority of sciatica cases respond to conservative care when properly diagnosed and helped.

Return to Your Life

Golf, gardening, playing with grandkids - return to activities you've been avoiding because of pain.
PATIENT EXPERIENCES

People Who Found the Source of Their Sciatica

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In my case, life-saving care after many other doctors told me there was nothing they could do for me. All the staff is extremely professional, helpful, and knowledgeable. Dr. Nepute Is seriously my new hero
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Big Guy
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All the workers take excellent care of the patients.
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James Christian
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Always a positive atmosphere.
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Larry Wylie
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everyone was so nice and was very courteous when working with me
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gina loewenstein
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Everyone there is awesome. John and Mike know how to work on my neck and I have had neck problems my whole life. I feel better everutime I leave. Can’t recommend enough.
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Peter P
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It was so amazing!
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Chloe Smith
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Want to get on or get back on the road to health? Tired of being tired? Tired of addressing symptoms instead of what causes them? This is the place that helps the whole body. Dr Eric’s brain is a catalog of all things health. His people are top notch. A special shout-out for Mandy who went above and beyond today. Thanks to all your caring hearts.
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Beverly M
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Finding Dr Nepute has been such a blessing for my family. His whole team approach is great. He has helped me get through the pain of a car accident. He know what he is doing and has a great team that helps. I highly recommend him.
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Janice Echols
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The staff was so professional and organized. There was no long wait time and Dr. Nepute was very focused on the best way to get me well again.
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Jeannie Holder
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I am so overly impressed with Dr. Nepute, the staff, and the care they have given me. I fly in from Texas to specifically be treated by Nepute Wellness center. They discovered issues that had been missed and overlook by mainstream doctors for years that were all treatable through diet and non-harmful supplements, unlike most doctors who want to push harmful pharmaceuticals. Their staff is friendly, caring, and compassionate! I highly recommend Nepute Wellness to anyone, especially those who have struggled with health issues that have been unresolved by mainstream doctors and meds! Thanks Dr Nepute and Staff!
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Andy
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Every staff member, every doctor and especially Dr. Nepute are some of the most upbeat, caring, professional individuals you’ll ever find in one place. Dr Nepute has created a culture with his staff where everyone there operates from a perspective of helping every patient live their lives with health and wellness. Whether you need a simple adjustment or you’re dealing with something more serious like an autoimmune disease or even cancer doctor Nepute and his staff can help. I would highly recommend anyone to go there if there’s ever an issue with anything in their health.
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Pat Marlow
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Dr. Eric Nepute and his staff are exceptional. If you want to get to the root of your health issues, and not just medicate yourself forever, GO SEE DR. E! Regardless of age. My youngest child had digestive and GI issues for years, and after a few months of seeing Dr. Nepute and his staff, my child is healthier, happier and can be a kid again. It doesn’t matter what your health issue is, stress, pain, GI, hormone imbalance, back/neck issues, fatigue, weight gain, cholesterol, high blood pressure, etc. they will get to the bottom of it. I thank God for doctors like Dr. Nepute who are dedicated to HEALTH care, and not just medical care or sick care. They strive to help heal their patients for good, so we don’t have to depend on frequent visits to the doctor for refills and short-term solutions. Thank you Dr. Nepute & Staff. You truly are changing lives every day!
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Jennifer Olson
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Nepute wellness Center is by far the best care I’ve experienced after being blessed to have had the best medical care from two different hospitals, and several injuries! I have been in the hospital 2 times in my life for a year both times. I’ve had multiple broken bones, struck by lightning. Several years later I was electrocuted by7200 volts, while working on a radio tower and a 40 ft fall. I’ve had several people who have known me speak that I am as tough as they come! But I tell you it’s the Grace of God who has brought me through these trials, moreover, to Nepute Wellness Center. My body has dealt with pain and arthritis for decades, and I am without a doubt a man of faith, and I have already seen results in a short amount of time. I have been blessed to find a entire group of people who care about people more than the bottom line. Pastor Jerry T.McClain
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Jerry McClain
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Dr Nepute and his staff, are ALL professional, courteous and personable.
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Ray Lewis
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One of the best in town! Attentive and knowledgeable and focused on seeing & retaining results.
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Patricia D. Johnson - Pope
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I was very impressed with the whole process my first visit and equally impressed with my second visit as they new my name very personable.
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Errands Unlimited (EU)
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Doc and his staff have completely changed my life. I have been suffering from chronic pain and inflamation. I have been going there for several years now. Dr. Eric, Dr. Rachel, Dr. Patric and staff have been extremely helpful. I have learned how to stay healthy and how to heal. I am in my sixties and very active. I plan on staying that way with the help of Nepute wellness. Over the years I have used traditional medicine only to be given pills that mask the pain. Neputi wellness has given me a holistic path to getting heathy and staying well. This type of wellness takes time. Have patience. You will be amazed ! Update 8/1/25 I just wanted to share that I have been taking the biolimitlist Neuro Reboot. My chronic pain has decreased to almost nothing. Especially in my lower back. This has allowed me to live the active life that I am accustomed to. I have been trying to avoid medications at all costs but was starting to give in. This product is working well. In my case, it took almost 60 days. But from then on, it was amazing. I noticed the first week I was sleeping better. The pain in my joints was starting to ease. My back, however, took a longer time. In my opinion, it is worth the money. And many thanks to doc and his amazing staff!
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Tony Frisella
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I had a wonderful experience at Dr Nepute’s Wellness Center. They are all very thorough and everyone working there are so nice. I’m excited for my body to heal itself!
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Daphne Covert
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The place is great. They truly care about your overall well being and not just your back.
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Sean Geoghegan
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Very friendly very thorough. I give a better reverie later as I’m with them longer to see if the help with my stomach issues. Ok I have CB been with them a year now. My stomach issues have completely turned around I’m eating much better. My blood work is much better. I plan on sticking with them. If you do what they say. And talk to them about your problems they can help you.
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guy donahoo
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Excellent service, diligent care and courteous workers. They make you feel at home here.
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José Jacinto
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I’ve been a client of the Nepute Wellness Center for probably 7 years now. Everyone on staff is super friendly and genuinely care about how you’re doing. I go weekly and just love that I do not have to make a specific appointment time. They do appreciate when you try to come on the same day each week. If you’re not able, it’s not a big deal. Nepute’s is such a multipurpose facility. They have taught me so much about nutrition along with different exercises I can do throughout the week. They are able to take X-rays and draw blood. This helps me keep an eye on my levels and numbers and catch anything that’s a little off before it becomes serious. They also have a nurse practitioner on staff at the facility in case you have some other issue like an earache, a rash, etc. The whole time I’ve been there I have had no need for a primary physician. . Oh, the babies and kids….I love watching them be adjusted. I wish I would’ve known about chiropractics when my kids were little.
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Dina Moore
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Great to be back
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Vicki Seel
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Love everyone there. Great adjustments and help. The knowledge they have to help you through so much is impressive. Started there 9 years ago and put my life back on track. I’m back this year to help with another issue, again I am feeling better then I have in a decade!
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Shannon Kahrhoff
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They are all wonderful
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Shonna Morrison
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Sciatica treatment process — functional medicine wellness approach at Nepute Wellness, neputewellness.com
HOW IT WORKS

Test, Don't Guess: Mapping Your Sciatic Nerve Compromise

We do not guess which level is compressed. Structural imaging, neurological assessment, and orthopedic testing map the exact source of nerve irritation — whether it is disc herniation, stenosis, or a mechanical misalignment putting pressure where it should not be.

Xray shoulders chest | Nepute Wellness
STRUCTURAL DIAGNOSTIC IMAGING

X-Rays

X-Rays: The Structural Foundation of Your Treatment Plan
Neck stretch | Nepute Wellness
NON-SURGICAL DISC AND SPINE RELIEF

Spinal Decompression Therapy

Spinal Decompression: A Non-Surgical Path for Disc Problems
Physical therapy treatment | Nepute Wellness
MOVEMENT REHABILITATION AND RECOVERY

Physical Therapy

Physical Therapy That Rebuilds How Your Body Moves
Chiro back adjustment | Nepute Wellness
STRUCTURAL SPINAL CORRECTION

Chiropractic Care

Chiropractic Care That Finds the Misalignment Behind Your Pain
YOUR QUESTIONS ANSWERED

Common Questions About Sciatica and Nerve Pain

The Seven Stages of Disconnection is a framework used at Nepute Wellness to help patients understand how health problems develop over time. Rather than viewing symptoms as isolated issues, this mod

Absolutely. Nepute Wellness serves patients from around the world through expanded virtual appointments via Zoom. International patients can access the same level of care, including home-shippable testing kits, virtual consultations (15, 30, or 60 minutes), and recorded Reports of Findings.

For those who prefer an in-person visit, our center is located in St. Louis, Missouri. Our team can help coordinate travel logistics for patients coming from out of state or internationally.

No referral is needed. Nepute Wellness operates outside the traditional insurance-based healthcare model, which means you can schedule directly without a physician referral. Whether you’re local to St. Louis or connecting virtually from anywhere in the world, you can book your consultation through our website.

Simply choose the examination tier that best fits your health needs and budget, and our team will guide you through the rest of the process.

Your first visit to Nepute Wellness is designed to feel warm and family-like, not clinical or intimidating. Depending on your chosen examination tier (Basic, Moderate, or Advanced), you’ll undergo

Nepute Wellness recommends BioLimitless supplement formulas as part of personalized wellness plans. Key formulas include Detox Pro Plus (detoxification support), Master Microbiotics (gut health), C

In-person examination deposits ($50) are non-refundable but may be applied toward rescheduling. Virtual consultation fees are non-refundable once the appointment has taken place. If you need to cancel or reschedule, please contact us at least 24 hours in advance.

BioLimitless products are subject to the BioLimitless return policy. Education materials and training courses are non-refundable once accessed. For full details, visit our Refund & Returns page at neputewellness.com.

Nepute Wellness offers three tiers of virtual one-on-one appointments via Zoom, available to patients worldwide:

  • 15-Minute Quick Hit ($42): Focused check-in or targeted question session
  • 30-Minute Moderate Dive ($242): In-depth review of specific concerns or test results
  • 60-Minute Deep Dive ($420): Comprehensive consultation covering full health assessment

All virtual visits include access to home testing kits that can be shipped directly to you, and your Report of Findings session is recorded so you can review it anytime.

“Selfcare as Healthcare” is one of the guiding mantras at Nepute Wellness. It represents the belief that true healthcare starts with empowering you to take an active role in your own healing and your family’s health, rather than passively depending on the traditional sick-care system.

At Nepute Wellness, this means educating you about root causes, providing tools and resources for ongoing wellness, and giving you the knowledge to make informed decisions about your health journey. Our goal is to move you from confusion and overwhelm to certainty and empowerment.

The Health Investment Plan is how Nepute Wellness frames the cost of care, as an investment in your long-term wellness rather than an expense for managing sickness. During your Day Two Report of Fi

“Blocked, not broken” is a core principle at Nepute Wellness. It means that in many cases, the body isn’t permanently damaged, it’s experiencing interference or blockages that prevent it from funct

Physiology Doesn't Lie:
Symptoms are your body's signals, NOT your diagnoses. Real testing reveals the real cause - and your real path, far away from simply treating those symptoms.
Connect From Anywhere
Expert guidance one-on-one, and without the travel! Limited availability virtual consultations with Dr. Eric Nepute are now available for those who can't visit Nepute Wellness's St. Louis clinic in person.
Cell Signals, Detox Pro Plus & Master Microbiotics
Detox, gut health, and cellular communication. The three pillars of foundational wellness.
Ready to Discover The Root Cause of Your Symptoms?
Comprehensive testing reveals what's actually happening in your body. No more guessing, and no more just "managing your symptoms". Its time to get to the root of your health concerns.
Unlock Your Genetic Blueprint
Your DNA reveals how your body is designed to function. Stop guessing. Start knowing.
Direct Nutrients, Maximum Absorption
You may have heard of a Myer's cocktail or a B-12 injection. At Nepute Wellness, we offer these and more, including custom formulations based on your bodies specific needs.